CCKBR is a potential target of miR-148b in SGC-7901, MGC-803, BGC-823 cells. (A), analysis of luciferase activity of five possible target genes with miR-148b mimics or NC in MGC-803 cells. (B), analysis of luciferase activity of pGL3-CCKBR-3'UTR, pGL3-CCKBR-3'UTR-poorly conserved, pGL3-CCKBR-3'UTR-conserved and positive control (PC) with miR-148b mimics or NC in MGC-803, SGC-7901 and BGC-823 cells. (C&D), Western blot and qRT-PCR were used to monitor the expression level of CCKBR in MGC-803 cells 48 h after transfection with miR-148b mimics or NC. (E), Effects of knockdown of the CCKBR gene on cell proliferation in MGC-803 cells.