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Table 1 Associations between the expression of miR-148b with clinicopathological features in 106 patients with gastric cancer

From: MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation

 

n

miR-148b a

Sex

  

   Male

80

0.28(0.08-1.26)

   Female

26

0.47(0.25-1.24)

P

 

0.272

Age (years)

  

   ≤65

65

0.41(0.10-1.24)

   > 65

41

0.27(0.08-1.26)

P

 

0.500

Tumor size (cm)

  

   < 6

73

0.46(0.13-1.47)

   ≥6

33

0.23(0.05-0.43)

P

 

0.027*

Macroscopic type

  

   Early stage

3

1.82(1.67-1.85)

   Borrmann I+II

9

0.50(0.26-1.01)

   Borrmann III+IV

94

0.31(0.08-1.16)

P

 

0.098

Histologic grade

  

   Good

23

0.31(0.10-0.61)

   Poor

83

0.41(0.08-1.28)

P

 

0.626

pT stage

  

   T1+T2

51

0.39(0.09-1.27)

   T3+T4

55

0.36(0.08-1.23)

P

 

0. 985

pN stage

  

   N0

25

0.28(0.08-0.69)

   N1

34

0.39(0.08-0.94)

   N2

29

0.47(0.20-1.70)

   N3

18

0.17(0.05-0.64)

P

 

0.171

pTNM stage

  

   I

20

0.35(0.09-0.66)

   II

22

0.33(0.08-0.94)

   III

39

0.43(0.17-1.27)

   IV

25

0.27(0.06-3.13)

P

 

0.821

Invasion into lymphatic vessels

  

   Negative

77

0.41(0.10-1.30)

   Positive

29

0.27(0.06-1.00)

P

 

0.346

  1. a Median of relative expression, with 25th-75th percentile in parenthesis.
  2. *Indicated statistical significance (P < 0.05).