Skip to main content
Figure 2 | Molecular Cancer

Figure 2

From: Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer

Figure 2

Influence of Bmi-1 expression on the overall survival. (A) The cumulative overall survival exhibited a significant difference based on Bmi-1 expression, assessed by Kaplan-Meier curves in primary breast cancer tissues (***P = 0.001). (B) No difference in the overall survival curve was observed according to Bmi-1 expression in the triple negative phenotype (TNP, ER-, PR-, and HER-2-) subgroup (P = 0.483). (C, D, E, F) High Bmi-1 expression was correlated with unfavorable prognosis irrelevant of the presence of ER (**P = 0.003, *P = 0.041) or PR (**P = 0.010, *P = 0.028). (G, H) The survival curves were significantly different according to Bmi-1 expression in the HER-2 positive panel (*P = 0.018), but not in HER-2 negative panel (P = 0.701).

Back to article page

Molecular Cancer

ISSN: 1476-4598