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Table 1 The percentage of positive cells and staining intensity of Bmi-1 expression related to clinicopathologic features

From: Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer

 

Percentage of Positive Cells

Staining Intensity

 

1

2

3

4

1

2

3

4

 

N

N

N

N

N

N

N

N

 

(%)

(%)

(%)

(%)

(%)

(%)

(%)

(%)

Age

        

   ≤45 year

11

38

20

30

5

33

35

26

 

(11.1)

(38.4)

(20.2)

(30.3)

(5.1)

(33.3)

(35.4)

(26.3)

   >45 year

16

40

21

64

5

46

54

36

 

(11.3)

(28.4)

(14.9)

(45.4)

(3.5)

(32.6)

(38.3)

(25.5)

T Classification

        

   T1

8

21

0

16

5

23

8

9

 

(17.8)

(46.7)

(0.0)

(35.6)

(11.1)

(51.1)

(17.8)

(20.0)

   T2

16

36

23

60

4

45

52

34

 

(11.9)

(26.7)

(17.0)

(44.4)

(3.0)

(33.3)

(38.5)

(25.2)

   T3

4

16

14

18

2

9

26

15

 

(7.7)

(30.8)

(26.9)

(34.6)

(3.8)

(17.3)

(50.0)

(28.8)

   T4

0

7

5

8

0

5

9

6

 

(0.0)

(35.0)

(25.0)

(40.0)

(0.0)

(25.0)

(45.0)

(30.0)

N Classification

        

   N0

18

35

6

31

6

44

24

16

 

(20.0)

(38.9)

(6.7)

(34.4)

(6.7)

(48.9)

(26.7)

(17.8)

   N1

10

35

28

59

5

30

57

40

 

(7.6)

(26.5)

(21.2)

(44.7)

(3.8)

(22.7)

(43.2)

(30.3)

   N2

0

6

6

10

0

5

10

7

 

(0.0)

(27.3)

(27.3)

(45.5)

(0.0)

(22.7)

(45.5)

(31.8)

   N3

0

4

2

2

0

3

4

1

 

(0.0)

(50.0)

(25.0)

(25.0)

(0.0)

(37.5)

(50.0)

(12.5)

M Classification

        

   M0

27

67

30

83

10

72

79

46

 

(13.0)

(32.4)

(14.5)

(40.1)

(4.8)

(34.8)

(38.2)

(22.2)

   M1

1

13

12

19

1

10

16

18

 

(2.2)

(28.9)

(26.7)

(42.2)

(2.2)

(22.2)

(35.6)

(40.0)

Clinical Stage

        

   I

3

14

0

6

2

16

2

3

 

(13.0)

(60.9)

(0.0)

(26.1)

(8.7)

(69.6)

(8.7)

(13.0)

   II

21

33

6

34

7

41

30

16

 

(22.3)

(35.1)

(6.4)

(36.2)

(7.4)

(43.6)

(31.9)

(17.0)

   III

3

20

24

43

1

15

47

17

 

(3.3)

(22.2)

(26.7)

(47.8)

(1.1)

(16.7)

(52.2)

(30.0)

   IV

1

13

12

19

1

10

16

18

 

(2.2)

(28.9)

(26.7)

(42.2)

(2.2)

(22.2)

(35.6)

(40.0)

ER Presence

        

   Negative

19

37

23

42

8

39

42

32

 

(15.7)

(30.6)

(19.0)

(32.7)

(6.6)

(32.2)

(34.7)

(26.4)

   Positive

9

43

19

60

3

43

53

32

 

(6.9)

(32.8)

(14.5)

(45.8)

(2.3)

(32.8)

(40.5)

(24.4)

PR Presence

        

   Negative

16

30

23

38

5

33

40

29

 

(15.0)

(28.0)

(21.5)

(35.5)

(4.7)

(30.8)

(37.4)

(27.1)

   Positive

12

50

19

64

6

49

55

35

 

(8.3)

(34.5)

(13.1)

(44.1)

(4.1)

(33.8)

(37.9)

(24.1)

HER-2 Presence

        

   Negative

9

12

8

22

4

17

14

16

 

(17.6)

(23.5)

(15.7)

(43.1)

(7.8)

(3.3)

(27.5)

(31.4)

   Positive

12

30

16

50

5

34

38

31

 

(11.1)

(27.8)

(14.8)

(46.3)

(4.6)

(31.5)

(35.2)

(28.7)

  1. Four categories of the percentage of positive cells: 1: ≤5%; 2: 6%-35%; 3: 36%-70%; 4: ≥71% (40X). Four categories of the staining intensity: 1: negative; 2: weak; 3: moderate; 4: strong.