Skip to main content

Table 3 Correlation between Bmi-1 expression and the clinicopathologic features of breast cancer

From: Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer

 

Bmi-1 Expression

Total

χ 2

P-value

 

Low

High

   
 

N (%)

N (%)

N (%)

  

Age

   

0.36

0.551

   ≤45 year

26 (26.3)

73 (73.7)

99 (41.2)

  

   >45 year

42 (29.8)

99 (70.2)

141 (58.8)

  

T Classification

   

30.92

<0.001

   T1

26 (57.8)

19 (42.2)

45 (17.9)

  

   T2

35 (25.9)

100 (74.1)

135 (53.6)

  

   T3

9 (17.3)

43 (82.7)

52 (20.6)

  

   T4

0 (0.0)

20 (100.0)

20 (7.9)

  

N Classification

   

46.45

<0.001

   N0

48 (53.3)

42 (46.7)

90 (35.7)

  

   N1

20 (15.2)

112 (84.8)

132 (52.4)

  

   N2

0 (0.0)

22 (100.0)

22 (8.7)

  

   N3

2 (25.0)

6 (75.0)

8 (3.2)

  

M Classification

   

14.87

<0.001

   M0

68 (32.9)

139 (67.1)

207 (82.7)

  

   M1

2 (4.4)

43 (95.6)

45 (17.9)

  

Clinical Stage

   

82.06

<0.001

   I

16 (69.6)

7 (30.4)

23 (9.1)

  

   II

48 (51.1)

46 (48.9)

94 (37.3)

  

   III

4 (4.4)

86 (95.6)

90 (35.7)

  

   IV

2 (4.4)

43 (95.6)

45 (17.9)

  

ER Presence

   

1.53

0.217

   Negative

38 (31.4)

83 (68.6)

121 (48.0)

  

   Positive

32 (24.4)

99 (75.6)

131 (52.0)

  

PR Presence

   

0.04

0.837

   Negative

29 (27.1)

78 (72.9)

107 (42.5)

  

   Positive

41 (28.3)

104 (71.7)

145 (57.5)

  

HER-2 Presence

   

0.71

0.400

   Negative

17 (33.3)

34 (66.7)

51 (32.1)

  

   Positive

29 (26.9)

79 (73.1)

108 (67.9)

  
  1. Four categories of the percentage of positive cells: 1: ≤5%; 2: 6%-35%; 3: 36%-70%; 4: ≥71% (40X).
  2. Four categories of the staining intensity: 1: negative; 2: weak; 3: moderate; 4: strong.
  3. Final score = score of percentage of positive cells × score of staining intensity. If the final score was >4, Bmi-1 expression was considered high, otherwise, Bmi-1 expression was considered low.