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Figure 8 | Molecular Cancer

Figure 8

From: A fiber-modified adenoviral vector interacts with immunoevasion molecules of the B7 family at the surface of murine leukemia cells derived from dormant tumors

Figure 8

Cell surface status of B7 molecules upon Ad5FB4 internalization. DA1-3b/d365 cells in suspension were incubated for 90 min at 4°C without (open bars) or with Ad5FB4 vector (filled bars) at 5,000 or 10,000 vp/cell. Cells were transferred to 37°C to allow for Ad5FB4 endocytosis and entry. The presence of B7-H1 and B7.1 molecules at the cell surface was assessed by flow cytometry in control cells (open bars), in cells taken after vector attachment at 4°C (grey bars), and in cells taken after 10 min at 37°C (black bars). Results shown are MFI. Symbols: *, p < 0.05.

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Molecular Cancer

ISSN: 1476-4598