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Figure 1 | Molecular Cancer

Figure 1

From: Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

Figure 1

Predictive In Silico Virtual tumor platform generated results. A, The chemical structure of plumbagin. B, The figure illustrates a high-level view of the maze of interactions and cross-talks present in the Virtual Tumor Cell platform. C, The figure illustrates the percentage reduction in CXCR4 and VEGFA with 50% and 100% inhibition of NF-κB in MDA-MB-231 (breast cancer) and AGS (gastric cancer) aligned virtual tumor cells. D, The figure illustrates the percentage reduction in metastatic tumor markers- CDH1 and Cathepsin B with 50% and 100% inhibition of NF-κB activation in the two tumor baselines.

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