Skip to main content

Advertisement

Table 3 Univariate and multivariate analyses of relationship between DSF and TGase 2 expression or clinicopathologic variables by Cox proportional hazard regression model (n = 429)

From: Transglutaminase 2 as an independent prognostic marker for survival of patients with non-adenocarcinoma subtype of non-small cell lung cancer

  Univariate analysis Multivariate analysis
  Hazard ratio 95% CI p-value Hazard ratio 95% CI p-value
Age 1.001 0.986-1.016 0.889    
Gender       
   Male 1 1     
   Female 1.107 0.794-1.542 0.549    
Histology    0.063    0.072
   Adenocarcinoma 1 1   1   
   Squamous carcinoma 0.718 0.521-0.991 0.044 0.701 0.487-1.008 0.056
   Others 1.200 0.705-2.042 0.501 1.214 0.710-2.076 0.478
Differentiation    0.172    
   Well 1 1     
   Moderate 1.424 0.862-2.354 0.168    
   Poorly 1.699 0.977-2.955 0.061    
Smoking status    0.165    
   Non-smoker 1      
   Ex-smoker 1.060 0.720-1.560 0.769    
   Current smoker 0.766 0.535-1.096 0.144    
T-Stage    0.044    0.012
   1 1 1   1 1  
   2 1.323 1 0.879-1.992 0.180 1.463 0.962-2.224 0.069
   3-4 1.898 1.143-3.150 0.013 2.209 1.308-3.731 0.003
N-Stage    <0.001    <0.001
   0 1 1   1 1  
   1 1.613 1.116-2.330 0.011 1.625 1.118-2.363 0.011
   2-3 2.121 1.459-3.084 <0.001 2.074 1.422-3.025 <0.001
TGase 2 expression    0.039    0.086
   Negative 1 1   1 1  
   Intermediate 1.230 0.846-1.789 0.277 1.111 0.752-1.642 0.597
   Strong 1.595 1.112-2.287 0.011 1.554 1.046-2.311 0.029
  1. In the multivariate analysis, variables including histology, T-stage and N-stage (those showing p < 0.10 in the univariate analysis) were considered.