Knockdown of CTGF expression inhibits the growth of gastric cancer cells. A. Colony formation assay. B. MTT proliferation assay. C. Knockdown of CTGF down regulated the mRNA level of cyclin D1. D. Knockdown of CTGF down regulated the protein level of cyclin D1. PSC1/PSC2+CM of SGC7901: PSC1 or PSC2 cells were incubated with conditioned medium (CM) of SGC7901. All results were reproducible in three independent experiments. *P < 0.05 as compared to control (control is SGC7901).