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Figure 4 | Molecular Cancer

Figure 4

From: L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer

Figure 4

L1CAM in A549. A) Stimulation of A549 cells with TGF-beta1 induces a mesenchymal phenotype whereas HGF does not alter cell morphology. Note that TGF-beta1 treatment affected the proliferation of A549 cells. B/C) A549 cells stimulated with TGF-beta1 show an EMT phenotype and increased L1CAM expression on mRNA and protein level. One representative experiment of n = 3 is shown. GAP-DH loading control. D) Matrigel invasion of A549 cells is enhanced by TGF-beta1 stimulation. The error bars represent mean values ± SEM. One representative experiment of n = 3 is shown.

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