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Figure 4 | Molecular Cancer

Figure 4

From: HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy

Figure 4

Antitumor efficacy of viruses on Huh-7 tumor xenografts in nude mice. (A) Ad.SPDD-HCCS1 and Ad.SPDD-HCCS1HA suppress the growth of Huh-7 tumors in vivo. The tumor volumes (mean+SD, n = 6) were measured and estimated every four days. (B) The ratios of surviving mice during the observation period in groups treated with different adenoviruses. (C) H&E staining and immunohistochemical staining of tumor sections using anti-hexon and anti-HA tag antibodies. Representative images are shown at 400 × magnification for the different samples Scale bar = 100 μm. (*: P < 0.05).

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Molecular Cancer

ISSN: 1476-4598