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Figure 1 | Molecular Cancer

Figure 1

From: Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation

Figure 1

Expression of Notch Receptors and Ligands in Pancreas Cancer. (A) Representative examples of some pancreas tumors expressing Delta-like 4 (DLL4), Jagged1(J1), Notch3 (N2), Notch3 (N3), and Notch4 (N4) by IHC. No tumor expressed Notch1 (N1), but its expression can be detected in blood vessels (arrow). (B) A representative example of a pancreas tumor expressing high level of EGFR. While the expression of Notch ligands and receptors does not correlate with clinical characteristics, Notch3 expression correlates positively with that of Jagged1 (C) and that of EGFR (D).

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Molecular Cancer

ISSN: 1476-4598