Table 2 Overview of the main features of the candidate genes. Human Entrez Gene ID is shown in the last column.
From: Identification of early molecular markers for breast cancer
Symbol | Name | Go terms: biological process; molecular function | GO terms: cellular component | Entrez GeneID |
|---|---|---|---|---|
MUC1 | mucin 1, cell surface associated | hormone activity | extracellular region, nucleus, cytoplasm, integral to membrane | 4582 |
SPP1 | secreted phosphoprotein 1 | ossification, cell adhesion; cytokine activity, protein binding | extracellular region | 6696 |
RRM2 | ribonucleotide reductase M2 polypeptide | DNA replication, deoxyribonucleoside diphosphate metabolic process, oxidation reduction; ribonucleoside-diphosphate reductase activity, iron ion binding, protein binding, oxidoreductase activity | cytoplasm, cytosol | 6241 |
FOXM1 | forkhead box M1 | regulation of transcription, DNA-dependent, vasculogenesis, positive regulation of cell proliferation; DNA binding, transcription factor activity, protein binding | nucleus | 2305 |
EXO1 | exonuclease 1 | DNA repair, mismatch repair, DNA recombination, immune response, meiosis; DNA binding, catalytic activity, exonuclease activity, endonuclease activity, ribonuclease H activity, protein binding, hydrolase activity | nucleus | 9156 |
DEPDC1 | DEP domain containing 1 | signal transduction, intracellular signaling cascade; GTPase activator activity | intracellular, nucleus | 55635 |
NUSAP1 | nucleolar and spindle associated protein 1 | mitotic sister chromatid segregation, cell cycle, mitosis, establishment of mitotic spindle localization, cell division; DNA binding, microtubule binding | nucleus, cytoplasm, microtubule | 51203 |