Molecular Cancer

Table 1 IL-17 affects the production of inflammatory cytokines of HCC

From: IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma

	Huh7 (pg/ml)			SMMC7721 (pg/ml)
IL-17 (50 ng/ml)	-	+	p	-	+	p
IL-6	7.0 ± 1.5	40.5 ± 19.6	< 0.001	63.3 ± 33.8	380.9 ± 198.2	0.001
IL-1β	5.3 ± 0.4	5.53 ± 0.5	0.397	6.4 ± 1.6	5.6 ± 1.0	0.261
TNF-α	22.5 ± 2.3	21.3 ± 1.2	0.206	22.8 ± 3.3	26.6 ± 6.0	0.137
TGF-β	215.7 ± 51.9	206.5 ± 47.5	0.716	140.7 ± 83.2	143.6 ± 41.5	0.931
IL-8	25.4 ± 13.1	141.3 ± 133.9	0.029	208.9 ± 144.5	521.7 ± 208.3	0.004
G-CSF	10.9 ± 1.2	11.4 ± 2.0	0.575	20.3 ± 14.9	39.3 ± 28.1	0.112
GM-CSF	6.5 ± 0.5	8.3 ± 3.8	0.212	8.40 ± 2.23	15.3 ± 9.9	0.078
VEGF	2236.4 ± 300.3	3814.5 ± 1188.6	0.043	332.0 ± 157.7	557.8 ± 162.2	0.014
MMP2	327.6 ± 12.2	492.8 ± 44.5	< 0.001	351.4 ± 14.3	558.6 ± 91.2	< 0.001

ELISA-determined cytokine levels were expressed as mean ± SD. p-values were calculated by Student's t test.

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