Figure 2From: Efficient Blockade of Akt signaling is a determinant factor to overcome resistance to MatuzumabMatuzumab inhibits EGFR and HER2 phosphorylation, but not Akt and MAPK phosphorylation elicited by EGF. Effects of Matuzumab (100 μg/mL) on EGF-induced activation of EGFR (Tyr 845, 992, 1045 and 1068), HER-2/neu, Akt and ERK 1/2 on A431, Caski and C33A cells, detected by Western blotting.Back to article page