Skip to main content
Figure 1 | Molecular Cancer

Figure 1

From: Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer

Figure 1

Sensitivities of cell lines to rapamycin vary by up to three fold. A) Cells were treated with either control, or different doses of rapamycin and growth/proliferation was monitored using MTT assays. MTT readings after 48 hours are shown relative to control. B) Relative sensitivities to rapamycin are shown; these are the % reductions in growth/proliferation caused by 100 nM rapamycin. Data points represent means (+/- standard deviations) from five independent wells of cells within a representative experiment. Data from independent repeat experiments are presented in Additional file 2, Figure S1 to demonstrate the reproducibility of these measurements in each cell line.

Back to article page

Molecular Cancer

ISSN: 1476-4598