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Figure 2 | Molecular Cancer

Figure 2

From: Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer

Figure 2

Levels of 4E-BP1 phosphorylation do not predict rapamycin sensitivity. Expression of phospho-4E-BP1 (A), total 4E-BP1 (B) and eIF4E (D) was examined in the cell lines shown by Western blot. Relative ratios of phospho-4E-BP1 to total 4E-BP1 are shown in C. Equal masses of total protein were loaded in each lane as determined by triplicate measurements with colourimetric protein mass assays, and expression was quantified by densitometry.

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Molecular Cancer

ISSN: 1476-4598