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Figure 7 | Molecular Cancer

Figure 7

From: Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression

Figure 7

Phospho-SMAD3C and SKI expression in melanoma. Consecutive slides of two cutaneous melanoma metastases (A, B and C, D) were stained for phospho-SMAD3C (A, C) and SKI (B, D). The intense P-SMAD3C (A) and lack of SKI staining (B) in the first sample contrasts with the relatively low P-SMAD3C staining (C) associated with clear nuclear SKI staining (D) from the other sample, and suggests an inverse correlation between both staining intensities. Arrows in D indicate SKI-positive nuclei. Scale bars: 12,5 μm

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