Table 4 SKI detection in a panel of human melanocytic lesions.
From: Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression
SKI expression | ||||
|---|---|---|---|---|
Absent | Present | p-Value | ||
Nevi (n = 12) | 4 | 8 | 0.388a | |
Primary melanoma (n = 37) | ||||
Tumor thickness | Mean (mm) | 1.68 | 2.2 | |
95% CI | 1.02-2.35 | 0.63-3.78 | 0.427b | |
Level of invasion (Clark) | II | 8 | 1 | |
III | 7 | 2 | ||
IV | 10 | 3 | ||
V | 4 | 2 | 0.779c | |
all | 29 (74.4%) | 8 (21.6%) | ||
Growth pattern | SSM | 24 | 7 | |
NM | 2 | 1 | ||
ALM | 3 | 0 | 0.581c | |
Anatomical localization | Head&Neck | 2 | 1 | |
Trunk | 13 | 4 | ||
Extremities | 14 | 3 | 0.803c | |
Metastases (n = 27) | ||||
Site | Lymph node | 7 | 3 | |
Skin | 12 | 5 | 0.651d | |