Skip to main content

Table 1 List of the 76 selected genes

From: Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

Gene symbols Alternative symbols Chromosome location Genbank accession
Mitotic spindle formation (n = 16)
AURKA a Aurora-A, STK15, STK6 20q13.2-q13.3 NM_003600
AURKAIP1 AKIP 1p36.33 NM_017900
AURKB Aurora-B; Aurora-1, STK12 17p13.1 NM_004217
AURKC Aurora-C, STK13 19q13.43 NM_003160
BIRC5 Survivin 17q25 NM_001168
CDC20 Fizzy-R, fzy, p55CDC 1p34.1 NM_001255
CLASP1   2q14.2 NM_015282
CLASP2   3p22.3 NM_015097
FBXW7 AGO, hCDC4 4q31.3 NM_033632
FZR1 HCDH1 19p13.3 NM_016263
KNTC1 Rough Deal/ROD 12q24.31 NM_014708
RASSF1A   3p21.3 NM_007182
TPX2 C20orf 20q11.2 NM_012112
ZW10 Zeste-White 11q23.3 NM_004724
ZWILCH FLJ10036 15q22.31 NM_017975
ZWINT ZW10 interactor 10q21-q22 NM_007057
Centrosome cohesion and duplication (n = 2)
CEP250 CEP2, C-NAP1 20q11.22 NM_007186
NEK2 NLK1 1q31.2-q41 NM_002497
Kinetochore-mitotic spindle interaction (n = 19)
BUB1   2q14 NM_004336
BUB1B BUBR1 15q15 NM_001211
BUB3   10q26 NM_004725
CENPE CENP-E 4q24-q25 NM_001813
CSE1L CAS 20q13 NM_001316
FBXO5 Emi1 6q25-q26 NM_012177
MAD1L1 MAD1 7p22 NM_003550
MAD2L1 MAD2 4q27 NM_002358
MAD2L2 REV7, MAD2B 1p36 NM_006341
NDC80 HEC1 18p11.31 NM_006101
PRCC   1q21.1 NM_005973
RAE1   20q13.31 NM_003610
RAN   12q24.3 NM_006325
RCC1 CHC1, RCC1 1p36.1 NM_001269
TACC1   8p11 NM_006283
TACC2   10q26 NM_206862
TACC3   4p16.3 NM_006342
TTK MPS1 kinase 6q13-q21 NM_003318
UBD FAT10 6p21.3 NM_006398
CDK-cyclin complexes (n = 7)
CCNA1 Cyclin A1 13q12.3-q13 NM_003914
CCNA2 Cyclin A2 4q25-q31 NM_001237
CCNB1 Cyclin B1 5q12 NM_031966
CCNB2 Cyclin B2 15q21.2 NM_004701
CCNB3 Cyclin B3 Xp11 NM_033031
CDKN1A p21(WAF1/CIP1) 6p21.2 NM_000389
CDC2 CDK1 10q21.1 NM_001786
Sister chromatid separation - mitotic exit (n = 29)
ANAPC1 APC1 2q12.1 NM_022662
ANAPC10 APC10 4q31 NM_014885
ANAPC11 APC11 17q25.3 NM_016476
ANAPC2 APC2 9q34.3 NM_013366
ANAPC4 APC4 4p15.2 NM_013367
ANAPC5 APC5 12q24.31 NM_016237
ANAPC7 APC7 12q13.12 NM_016238
CDC16 APC6 13q34 NM_003903
CDC23 APC8 5q31 NM_004661
CDC26   9q32 NM_139286
CDC27 APC3 17q12-17q23.2 NM_001256
CDC34   19p13.3 NM_004359
ESPL1 Separase 12q13 NM_012291
HSPB1 HSP27 7q11.23 NM_001540
NEDD8   14q11.2 NM_006156
PLK1 Polo-like kinase 1 16p12.1 NM_005030
PPP1CA PPP1A 11q13 NM_002708
PPP1R2 Inh2 3q29 NM_006241
PTTG1 Securin 5q35.1 NM_004219
RAD21 SCC1, KIAA0078 8q24 NM_006265
RNF2 Ding 1q25.3 NM_007212
SMC1A SMC1L1 Xp11.22-p11.21 NM_006306
SMC1B SMC1L2 22q13.31 NM_148674
SMC3 CSPG6 10q25 NM_005445
STAG1 SA1 (stromal antigen 1) 3q22.2 NM_005862
STAG2 SA2 (stromal antigen 2) Xq25 NM_006603
UBE1C UBA3 3p24.3-p13 NM_003968
UBE2B UBE2B 5q23q-31 NM_003337
UBE2N   12q22 NM_003348
Double-strand break repair (n = 3)
MRE11A MRE11 11q21 NM_005590
BRCA1   17q21 NM_007294
BRCA2   13q12.3 NM_000059
  1. a Entrez Gene symbol