Table 1 List of the 76 selected genes
Gene symbols | Alternative symbols | Chromosome location | Genbank accession |
|---|---|---|---|
Mitotic spindle formation (n = 16) | |||
AURKA a | Aurora-A, STK15, STK6 | 20q13.2-q13.3 | NM_003600 |
AURKAIP1 | AKIP | 1p36.33 | NM_017900 |
AURKB | Aurora-B; Aurora-1, STK12 | 17p13.1 | NM_004217 |
AURKC | Aurora-C, STK13 | 19q13.43 | NM_003160 |
BIRC5 | Survivin | 17q25 | NM_001168 |
CDC20 | Fizzy-R, fzy, p55CDC | 1p34.1 | NM_001255 |
CLASP1 | 2q14.2 | NM_015282 | |
CLASP2 | 3p22.3 | NM_015097 | |
FBXW7 | AGO, hCDC4 | 4q31.3 | NM_033632 |
FZR1 | HCDH1 | 19p13.3 | NM_016263 |
KNTC1 | Rough Deal/ROD | 12q24.31 | NM_014708 |
RASSF1A | 3p21.3 | NM_007182 | |
TPX2 | C20orf | 20q11.2 | NM_012112 |
ZW10 | Zeste-White | 11q23.3 | NM_004724 |
ZWILCH | FLJ10036 | 15q22.31 | NM_017975 |
ZWINT | ZW10 interactor | 10q21-q22 | NM_007057 |
Centrosome cohesion and duplication (n = 2) | |||
CEP250 | CEP2, C-NAP1 | 20q11.22 | NM_007186 |
NEK2 | NLK1 | 1q31.2-q41 | NM_002497 |
Kinetochore-mitotic spindle interaction (n = 19) | |||
BUB1 | 2q14 | NM_004336 | |
BUB1B | BUBR1 | 15q15 | NM_001211 |
BUB3 | 10q26 | NM_004725 | |
CENPE | CENP-E | 4q24-q25 | NM_001813 |
CSE1L | CAS | 20q13 | NM_001316 |
FBXO5 | Emi1 | 6q25-q26 | NM_012177 |
MAD1L1 | MAD1 | 7p22 | NM_003550 |
MAD2L1 | MAD2 | 4q27 | NM_002358 |
MAD2L2 | REV7, MAD2B | 1p36 | NM_006341 |
NDC80 | HEC1 | 18p11.31 | NM_006101 |
PRCC | 1q21.1 | NM_005973 | |
RAE1 | 20q13.31 | NM_003610 | |
RAN | 12q24.3 | NM_006325 | |
RCC1 | CHC1, RCC1 | 1p36.1 | NM_001269 |
TACC1 | 8p11 | NM_006283 | |
TACC2 | 10q26 | NM_206862 | |
TACC3 | 4p16.3 | NM_006342 | |
TTK | MPS1 kinase | 6q13-q21 | NM_003318 |
UBD | FAT10 | 6p21.3 | NM_006398 |
CDK-cyclin complexes (n = 7) | |||
CCNA1 | Cyclin A1 | 13q12.3-q13 | NM_003914 |
CCNA2 | Cyclin A2 | 4q25-q31 | NM_001237 |
CCNB1 | Cyclin B1 | 5q12 | NM_031966 |
CCNB2 | Cyclin B2 | 15q21.2 | NM_004701 |
CCNB3 | Cyclin B3 | Xp11 | NM_033031 |
CDKN1A | p21(WAF1/CIP1) | 6p21.2 | NM_000389 |
CDC2 | CDK1 | 10q21.1 | NM_001786 |
Sister chromatid separation - mitotic exit (n = 29) | |||
ANAPC1 | APC1 | 2q12.1 | NM_022662 |
ANAPC10 | APC10 | 4q31 | NM_014885 |
ANAPC11 | APC11 | 17q25.3 | NM_016476 |
ANAPC2 | APC2 | 9q34.3 | NM_013366 |
ANAPC4 | APC4 | 4p15.2 | NM_013367 |
ANAPC5 | APC5 | 12q24.31 | NM_016237 |
ANAPC7 | APC7 | 12q13.12 | NM_016238 |
CDC16 | APC6 | 13q34 | NM_003903 |
CDC23 | APC8 | 5q31 | NM_004661 |
CDC26 | 9q32 | NM_139286 | |
CDC27 | APC3 | 17q12-17q23.2 | NM_001256 |
CDC34 | 19p13.3 | NM_004359 | |
ESPL1 | Separase | 12q13 | NM_012291 |
HSPB1 | HSP27 | 7q11.23 | NM_001540 |
NEDD8 | 14q11.2 | NM_006156 | |
PLK1 | Polo-like kinase 1 | 16p12.1 | NM_005030 |
PPP1CA | PPP1A | 11q13 | NM_002708 |
PPP1R2 | Inh2 | 3q29 | NM_006241 |
PTTG1 | Securin | 5q35.1 | NM_004219 |
RAD21 | SCC1, KIAA0078 | 8q24 | NM_006265 |
RNF2 | Ding | 1q25.3 | NM_007212 |
SMC1A | SMC1L1 | Xp11.22-p11.21 | NM_006306 |
SMC1B | SMC1L2 | 22q13.31 | NM_148674 |
SMC3 | CSPG6 | 10q25 | NM_005445 |
STAG1 | SA1 (stromal antigen 1) | 3q22.2 | NM_005862 |
STAG2 | SA2 (stromal antigen 2) | Xq25 | NM_006603 |
UBE1C | UBA3 | 3p24.3-p13 | NM_003968 |
UBE2B | UBE2B | 5q23q-31 | NM_003337 |
UBE2N | 12q22 | NM_003348 | |
Double-strand break repair (n = 3) | |||
MRE11A | MRE11 | 11q21 | NM_005590 |
BRCA1 | 17q21 | NM_007294 | |
BRCA2 | 13q12.3 | NM_000059 | |