Figure 1
From: miR-449 inhibits cell proliferation and is down-regulated in gastric cancer
Old Gastrin knockout mice develop gastric adenomas. Antrum sections isolated from 12-16 weeks old mice (left panel), 12 to 18 months old mice (middle panel) and older than 18 months mice (right panel), from wild type (upper panel) and Gastrin knockout mice (lower panel). Sections show adenoma development in antrum tissues in the Gastrin knockouts compared to the wild types.