Table 1 RB1 status of 30 cancer cell lines used for gene expression
Cell line | Tissue type | RB1 genetic status | RB1 functional status |
|---|---|---|---|
T-24 | bladder | wild-type | + |
U-2-OS | bone | wild-type | + |
SF268 | CNS | wild-type | + |
DLD-1 | colon | NA | + |
HCT-116 | colon | wild-type | + |
Hep G2 | liver | NA | + |
NCI-H460 | NSCLC | wild-type | + |
A549 | NSCLC | wild-type | + |
UACC-62 | melanoma | wild-type | + |
MDAH-2774 | ovary | NA | + |
PANC-1 | pancreas | NA | + |
SU.86.86 | pancreas | NA | + |
NCI-N87 | stomach | wild-type | + |
Hs 746T | stomach | NA | + |
KATOIII | stomach | wild-type | + |
SCC-25 | tongue | wild-type | + |
J82 | tongue | Δ21 2107-2A > G | - |
HeLa S3 | bladder | repressed by E7 | - |
DU-145 | cervix | stop: K175* | - |
TCCSUP | bladder | deletion: 1696_2787del1092 | - |
MDA-MB-436 | breast | frame shift: G203fs*8 | - |
MDA-MB-468 | breast | deletion: 265_2787del2523 | - |
SF-539 | CNS | deletion: T116fs*8 | - |
HeLa | cervix | repressed by E7 | - |
C-33A | cervix | deletion: 4aa in exon2 | - |
Lu-135 | SCLC | frame shift: R661fs*1 | - |
NCI-H128 | SCLC | frame shift: R418fs*2 | - |
NCI-H1417 | SCLC | stop: Y321* | - |
NCI-H69 | SCLC | stop: E748* | - |
NCI-H596 | NSCLC | frame shift: R661fs*1 | - |