Figure 3
Antitumour efficacy of the single mAbs in the intravenous JOK1-5.3 model. Kaplan-Meier curves showing survival fractions of SCID mice grafted by i.v. injection via the tail vein of 10 × 106 JOK1-5.3 cells and treated with i.v. injections of either mAb anti-CD5, anti-CD71 or anti-HLA-DR (0.25 mg on days +3, +5, +7 and +11) or irrelevant mouse IgG1 isotype. All treated groups are significantly different from the control groups p < 0.005). The study was performed twice. Data are presented as cumulative percentage of both experiments.