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Figure 4 | Molecular Cancer

Figure 4

From: Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia

Figure 4

Increased antitumour efficacy of the injection of two mAbs combination in the intraperitoneal JOK1-5.3 model. Kaplan-Meier curves showing survival fractions of SCID mice intraperitoneally grafted with JOK1-5.3 and treated with two i.p. injections of different combinations of two mAbs (0.25 mg of each mAb) at day 1 and 4: A, combination of anti-HLA-DR and anti-CD5, B, combination of anti-CD71 and anti-CD5 or C, combination of anti-HLA-DR and anti-CD71 mAbs. Combination treatments were compared with two i.p. injections of 0.5 mg from only one mAb at day 1 and 4, or PBS injected control mice. The study was performed twice. Data are presented as cumulative percentage of both experiments.

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