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Table 1 Percentage binding of 125I labelled purified mAbs to different leukaemia/lymphoma cell lines

From: Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia

mAbs

JOK1-5.3

JOK1

JURKAT

DAUDI

BL60.2

anti-CD5

61.6 (+/- 2.3)

< 1%

75.0 (+/- 1.8)

< 1%

< 1%

anti-CD71

47.2 (+/- 5.5)

n.d.

50.6 (+/- 6.5)

49.5 (+/- 2.6)

50.0 (+/- 2.6)

anti-HLA DR

56.1 (+/- 3.4)

50.7 (+/- 6.71)

< 1%

56.2 (+/- 13.0)

63.4 (+/- 20.1)

anti-CD20

41.0 (+/- 3.4)

40.8 (+/- 2.5)

> 1%

31.1 (+/- 5.6)

65.0 (+/- 6.2)

  1. The percentage of binding of each 125I-labelled mAb to increasing numbers of each target cell lines was measured. Results are expressed as % of specific binding extrapolated to an infinite number of target cells [44]
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Molecular Cancer

ISSN: 1476-4598