Skip to main content
Figure 6 | Molecular Cancer

Figure 6

From: HBx Sensitizes Cells to Oxidative Stress-induced Apoptosis by Accelerating the Loss of Mcl-1 Protein via Caspase-3 Cascade

Figure 6

Expression of HBx and Mcl-1 is inversely correlated in HBV-related HCC tissues. (A) The correlation of HBx and hMTH1 mRNA expression and (B) HBx and MnSOD mRNA expression in 22 HBV-positive HCC samples was shown. (C) Protein levels of Mcl-1, Bcl-xL and β-actin were determined by Western blot assay in 18 HBV-positive HCC samples. The relative protein expression of Mcl-1 and Bcl-xL was quantified and normalized to β-actin. The relative mRNA expression of HBx was also quantified and normalized to 18S rRNA. (D) The relationship between HBx and Mcl-1 expression or HBx and Bcl-xL expression in 30 HBV-positive HCC samples was shown. Correlation between two variables was calculated by Spearman rank correlation coefficient (r).

Back to article page

Molecular Cancer

ISSN: 1476-4598