Figure 6
From: RNA polymerase III transcription in cancer: the BRF2 connection
Oncomine analysis of BRF2 expression in breast carcinoma using COPA. As seen in Figure 3, BRF2 was overexpressed in a total of 50 analyses using an outlier analysis. COPA (cancer outlier profile analysis) analyzes a small subpopulation of samples which represent outliers within the datasets for significant expression and does not represent the majority of samples. We investigated BRF2 expression in several breast carcinoma studies based on the high number of analyses BRF2 was overexpressed in using COPA (Figure 3). Based on the COPA method, BRF2 is highly overexpressed across 17 breast carcinoma analyses in a subset of the patient samples used for each respective analysis. The red represents significant overexpression. The datasets used for this analysis and the number of patient samples used in each individual study are shown as well. (Oncomine database).