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Figure 2 | Molecular Cancer

Figure 2

From: MDM2 antagonists boost antitumor effect of androgen withdrawal: implications for therapy of prostate cancer

Figure 2

Combination effect of nutlin and androgen deprivation in vitro. LNCaP (A), 22Rv1 (B), and DU145 cells (C) were exposed to 5 μM Flutamide (FLU) and/or 5 μM Nutlin-3a in the presence of complete serum or charcoal stripped serum (CSS). Western blotting was used to monitor protein levels of Androgen receptor (AR) and the Annexin V assay to measure apoptotic response ± SD.

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Molecular Cancer

ISSN: 1476-4598