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Table 2 Differential gene expression relative to the corresponding gene of the paternal cell line.

From: Micro-RNA expression in cisplatin resistant germ cell tumor cell lines

 

Mean differential gene expression in cell line pairs

 

Mean differential gene expression in cell line pairs

 

NTERA-2-R/NTERA-2

NCCIT-R/NCCIT

2102EP-R/2102EP

 

NTERA-2-R/NTERA-2

NCCIT-R/NCCIT

2102EP-R/2102EP

Detector

fold-change

SEM

p-value

fold-change

SEM

p-value

fold-change

SEM

p-value

Detector

fold-change

SEM

p-value

fold-change

SEM

p-value

fold-change

SEM

p-value

hsa-miR-708

0.5

0.1

0.014

0.4

0.1

0.004

   

hsa-miR-525-3p

6.8

1.3

0.009

8.0

0.9

<0.001

   

hsa-miR-130b

0.5

0.1

0.096

      

hsa-miR-519a

6.8

1.0

0.008

6.0

0.9

0.081*

   

hsa-miR-455-5p

2.0

0.4

0.059

      

hsa-miR-518a-3p

6.9

1.1

0.004

7.2

0.3

<0.001

   

hsa-miR-193b

2.1

0.5

0.036

      

hsa-miR-520b

7.0

2.3

0.004

5.5

0.8

<0.001

   

hsa-miR-146a

2.1

0.3

0.1*

2.6

0.1

<0.001

   

hsa-miR-517b

7.2

1.2

0.003

6.4

1.5

0.006

   

RNU43

2.2

0.3

0.1*

      

hsa-miR-518b

7.3

0.4

<0.001

8.1

1.2

<0.001

   

hsa-miR-526b

2.2

0.4

0.061

      

hsa-miR-515-5p

7.8

1.0

0.005

5.6

0.3

<0.001

   

hsa-miR-302b

2.3

1.2

0.512

0.5

0.1

0.058

   

hsa-miR-145

   

0.0

0.0

<0.001

   

hsa-miR-524-3p

2.4

0.1

0.019

      

hsa-miR-100

   

0.1

0.0

<0.001

   

hsa-miR-10b

2.8

0.6

0.006

2.0

0.6

0.081*

2.7

0.5

0.126

hsa-miR-99a

   

0.1

0.0

<0.001

   

hsa-miR-205

2.9

0.5

0.004

0.5

0.1

0.034

   

hsa-miR-582-5p

   

0.2

0.0

<0.001

   

hsa-miR-518c

2.9

0.4

0.004

      

hsa-miR-125b

   

0.2

0.0

<0.001

0.4

0.0

0.012

hsa-miR-801

3.0

1.0

0.172

      

hsa-miR-450b-5p

   

0.4

0.0

0.038

   

hsa-miR-523

3.5

0.1

0.004

3.0

0.5

0.012

   

hsa-miR-302d

   

0.4

0.0

<0.001

   

hsa-miR-362-3p

3.7

1.7

0.026

   

2.4

0.8

0.132

hsa-miR-192

   

0.4

0.1

0.004

   

hsa-miR-520f

3.7

0.3

0.010

2.4

0.3

0.001

   

hsa-miR-218

   

0.5

0.1

0.030

0.3

0.0

<0.001

hsa-miR-520h

3.9

0.4

<0.001

7.1

0.7

<0.001

   

hsa-miR-335

   

0.5

0.1

0.062

   

hsa-miR-371-3p

4.0

0.3

<0.001

15.2

2.1

<0.001

   

hsa-miR-21

   

0.5

0.0

0.061

   

hsa-miR-373

4.1

0.7

0.006

12.0

2.9

<0.001

   

hsa-miR-576-3p

   

0.5

0.1

0.001

   

hsa-miR-519c-3p

4.3

0.3

0.008

3.2

0.3

0.001

   

hsa-miR-363

   

0.5

0.0

0.001

   

hsa-miR-522

4.3

0.7

0.002

6.4

0.4

0.002

   

hsa-miR-424

   

0.5

0.0

0.002

   

hsa-miR-526b

4.3

0.5

<0.001

8.3

2.3

0.002

   

hsa-miR-302a

   

0.5

0.0

0.003

   

hsa-miR-519b-3p

4.4

0.4

0.006

7.8

1.0

0.003

   

hsa-miR-194

   

0.5

0.2

0.078

   

hsa-miR-518d-5p

4.5

0.5

0.004

3.3

0.4

0.001

   

hsa-miR-221

   

0.5

0.1

0.034

   

hsa-miR-516b

4.5

0.4

0.002

3.1

0.5

0.002

   

hsa-miR-935

   

2.5

0.1

<0.001

   

hsa-miR-512-5p

4.6

1.3

0.021

6.3

0.8

0.001

   

hsa-miR-383

   

13.3

2.8

<0.001

   

hsa-miR-520c-3p

4.6

0.6

<0.001

5.6

0.5

0.002

   

hsa-miR-489

      

0.1

0.0

<0.001

hsa-miR-372

4.7

1.0

0.081*

16.3

2.0

<0.001

   

hsa-miR-365

      

0.3

0.1

<0.001

hsa-miR-512-3p

5.1

0.9

0.004

7.8

1.2

<0.001

2.1

0.2

0.024

hsa-miR-193a-5p

      

0.4

0.1

0.008

hsa-miR-518f

5.2

0.7

0.003

6.3

0.9

<0.001

   

hsa-miR-296-5p

      

0.4

0.0

0.003

hsa-miR-519d

5.2

0.7

0.001

7.0

2.6

0.003

   

hsa-miR-484

      

0.4

0.0

0.002

hsa-miR-517a

5.3

1.2

0.005

6.0

0.6

<0.001

   

hsa-miR-335*

      

0.5

0.0

0.007

hsa-miR-520g

5.8

0.6

0.005

7.5

1.5

<0.001

   

hsa-miR-34a

      

2.4

0.4

0.048

hsa-miR-517c

6.1

0.5

0.001

6.7

0.5

<0.001

   

hsa-miR-923

      

2.4

0.6

0.188*

hsa-miR-515-3p

6.4

0.2

<0.001

4.8

0.5

<0.001

   

hsa-miR-146b-5p

      

3.9

0.6

0.081

hsa-miR-518e

6.7

0.4

0.001

8.1

1.5

<0.001

   

hsa-miR-19b-1

      

5.7

3.5

0.081

  1. Differential gene expression (mean fold-change from three independent experiments) was calculated from gene expression measured in the chemoresistant cell line (-R added to the paternal cell line's name) relative to the corresponding gene of the paternal cell line. Genes are listed in ascending order of the NTERA-2 cell's fold-change followed by NCCIT and 2102EP values. P-values were calculated with t-test (equal variance and normal distributed data) and values with asterix with the MannWhitney rank sum test.
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Molecular Cancer

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