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Figure 3 | Molecular Cancer

Figure 3

From: Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth

Figure 3

Rhox5 is bivalent marked in ES cells, somatic cells and cancer cells. (A). Histone methylation marks (H3K4me2; H3K27me3 and H3K9me2) on Rhox5 promoter regions were determined by ChIP assays. Locations of ChIP-1 and ChIP-2 regions were illustrated in the cartoon of Fig. 1A. (B). Histone acetylation and methylation marks on promoter regions in cancer cells with Rhox5 expression at high (CT26) and low (EMT6) levels. (C). Quantification of the data from CT26 and EMT6 cells. Bars are mean with s.d.

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