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Table 2 Sp1 sites in demethylated tumour suppressor gene promoters

From: Epigenetic reprogramming of breast cancer cells with oocyte extracts

  RARB CST6 CCND2 CDKN2A
Number of demethylated CGs 8-13 1-8, 14-18, 25, 31 1-7, 21-28 1-9, 19-28
Number of demethylated CGs containing Sp1 sites 12 5, 12, 13 1, 2 9, 10, 22
Putative transcription factors binding sites contained in demethylated CGs NF-kappaB, c-Re1 GATA-1, Ahr/Arnt CREB, MYC, USF1, MAX, SRY, MZF-1 USF1, MZF-1, CP2
  1. Putative transcription factor binding sites as determined by TFSEARCH http://www.cbrc.jp/research/db/TFSEARCH.html.