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Table 2 Sp1 sites in demethylated tumour suppressor gene promoters

From: Epigenetic reprogramming of breast cancer cells with oocyte extracts

 

RARB

CST6

CCND2

CDKN2A

Number of demethylated CGs

8-13

1-8, 14-18, 25, 31

1-7, 21-28

1-9, 19-28

Number of demethylated CGs containing Sp1 sites

12

5, 12, 13

1, 2

9, 10, 22

Putative transcription factors binding sites contained in demethylated CGs

NF-kappaB, c-Re1

GATA-1, Ahr/Arnt

CREB, MYC, USF1, MAX, SRY, MZF-1

USF1, MZF-1, CP2

  1. Putative transcription factor binding sites as determined by TFSEARCH http://www.cbrc.jp/research/db/TFSEARCH.html.