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Figure 7 | Molecular Cancer

Figure 7

From: Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4

Figure 7

Induction of changes in mitochondrial function, total cellular protein, ATP activity and autophagy in H460 human non-small cell lung cancer cells following exposure to THR53 or chloroquine. A. Treatment with THR53 showing selective inhibition of ATP at 96 hours after initial exposure. B. Treatment of H460 with Chloroquine results in non-specific changes in all cell death parameters at 96 hours after initial exposure. C. THR53 treatment of H460 non-small cell lung cancer cells does not induce autophagy.

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Molecular Cancer

ISSN: 1476-4598