Skip to main content


Table 1 Proteins identified by LC-MS/MS of cut bands in the Ku86 complex

From: Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatin

Protein name1 Synonym1 Accession Number1 Theoretical MW (kDa)1 No. of Peptides2 Function3
ATP-dependent DNA helicase 2 subunit 1 Ku70 P12956 69.71 21 DNA repair
ATP-dependent DNA helicase 2 subunit 2 Ku86 P13010 82.57 20 DNA repair
FACT complex subunit SPT164 SPT16 Q9Y5B9 119.91 11 Nucleosome/transcription
Werner syndrome ATP-dependent helicase WRN Q14191 162.49 7 Helicase
Lamina-associated polypeptide 2 isoform alpha LAP2A P42166 75.36 7 DNA binding
DNA topoisomerase 1 TOP1 P11387 90.73 1 Chromatin binding
Poly (ADP-ribose) polymerase 1 PARP-1 P09874 112.95 1 DNA binding
ATP-dependent RNA helicase DDX17 Q92841 72.37 1 Helicase
  1. 1 as in the SWISS-PROT database, 2 number of peptide obtain by LC-MSMS analysis of the unique silver stained band shown in figure 1, 3 as in the Gene Ontology classification.