Figure 2
From: Rare human papillomavirus 16 E6 variants reveal significant oncogenic potential
Cell cycle profile of HPV16 E6 variants. The distribution of cells in G1, S and G2/M phases, obtained by flow cytometry, is demonstrated in A (histograms from a representative experiment) and B (mean values bars). Data with and without actinomycin D (AD) treatment (0.5 nM for 24 h) are shown. Differences in G1/S ratio are depicted in C. Mean values of at least three independent experiments are presented as average (mean) ± standard deviation (SD). Significance was tested by a one-way ANOVA test. A P value of < 0.05 was considered significant.