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Figure 4 | Molecular Cancer

Figure 4

From: Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells

Figure 4

Induction of irinotecan metabolism genes after CPT-11 and SN-38 treatment. LS180 and HepG2 cells were treated with 1 μg/ml CPT-11 or 10 ng/ml SN-38 for 24 h and quantitative RT-PCR were performed on irinotecan metabolism genes. Fold inductions were calculated relative to the mean expression of GAPDH and experiments were performed in triplicate. (a ND for not detected).

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Molecular Cancer

ISSN: 1476-4598