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Figure 4 | Molecular Cancer

Figure 4

From: Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas

Figure 4

Summary of genetic and epigenetic findings in colorectal cancers (test and validation sets). Red color: methylated (CNRIP1, FBN1, INA, MAL, SNCA, and/or SPG20), mutated (BRAF), and/or MSI positive samples. Green color: unmethylated, wt (BRAF), and/or MSS/MSI-low samples. Biomarker panel positive samples have co-methylation of two or more of the six biomarkers. The SPG20 promoter methylation status has previously been published in the same sample series [9].

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