Table 1 Histoclinical features of basal-like tumors (IPC and validation series)
From: Kinome expression profiling and prognosis of basal breast cancers
Characteristics (N) | Basal |
|---|---|
| Â | N = 591 |
| Â | N (% of evaluated cases) |
Age (445) | Â |
≤ 50 years | 215 (57%) |
> 50 years | 162 (43%) |
Histological type (256) | Â |
ductal | 234 (91%) |
lobular | 7 (3%) |
other* | 15 (6%) |
Pathological tumor size, pT (466) | Â |
pT1 | 115 (25%) |
pT2-4 | 351 (75%) |
Pathological lymph node status, pN (493) | Â |
negative | 314 (64%) |
positive | 179 (36%) |
Tumor grade (493) | Â |
SBR 1 | 14 (3%) |
SBR 2-3 | 479 (97%) |
IHC ER status (507) | Â |
negative | 411 (81%) |
positive | 96 (19%) |
IHC PR status (223) | Â |
negative | 199 (89%) |
positive | 24 (11%) |
IHC ERBB2 status (105) | Â |
negative | 86 (84%) |
positive | 19 (16%) |
Adjuvant chemotherapy (309) | Â |
no | 203 (66%) |
yes | 106 (34%) |
Adjuvant hormone therapy (322) | Â |
no | 237 (95%) |
yes | 13 (5%) |
Events (453)** | 183 (40%) |
5-year DFS (453)** | 61% |