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Table 1 Histoclinical features of basal-like tumors (IPC and validation series)

From: Kinome expression profiling and prognosis of basal breast cancers

Characteristics (N) Basal
  N = 591
  N (% of evaluated cases)
Age (445)  
≤ 50 years 215 (57%)
> 50 years 162 (43%)
Histological type (256)  
ductal 234 (91%)
lobular 7 (3%)
other* 15 (6%)
Pathological tumor size, pT (466)  
pT1 115 (25%)
pT2-4 351 (75%)
Pathological lymph node status, pN (493)  
negative 314 (64%)
positive 179 (36%)
Tumor grade (493)  
SBR 1 14 (3%)
SBR 2-3 479 (97%)
IHC ER status (507)  
negative 411 (81%)
positive 96 (19%)
IHC PR status (223)  
negative 199 (89%)
positive 24 (11%)
IHC ERBB2 status (105)  
negative 86 (84%)
positive 19 (16%)
Adjuvant chemotherapy (309)  
no 203 (66%)
yes 106 (34%)
Adjuvant hormone therapy (322)  
no 237 (95%)
yes 13 (5%)
Events (453)** 183 (40%)
5-year DFS (453)** 61%
  1. *4 metaplastic carcinomas, 4 mixed adenocarcnomas, 1 mucinous carcinoma, and 5 adenocarcinomas non otherwise specified. **out of these 453 patients with available follow-up, 193 did not received any systemic adjuvant treatment, 115 received adjuvant systemic therapy, no patient received adjuvant Trastuzumab, and data were unavailable for 145 patients.