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Figure 4 | Molecular Cancer

Figure 4

From: MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1

Figure 4

Knockdown of BMI-1 repressed in vitro cell proliferation and clone growth. A. Effects of BMI-1 repression on cell proliferation assessed by MTT assay in un-transfected HEC-50B-HI cells, HEC-50B-HI-BMI-1 shRNA and control shRNA cells. *P < 0.05. B. Colony formation was assessed following stable repression of BMI-1. *P < 0.05. C. Western immunoblot analysis of p16 protein expression in un-transfected HEC-50B-HI cells, HEC-50B-HI-BMI-1 shRNA cells and control shRNA cells. D. mRNA expression levels of SOX-2, KLF4 and MRP-1 in HEC-50B-HI-BMI-1 shRNA and control shRNA cells were determined by Real-time RT-PCR. Data represent the mean ± SE of three independent experiments.

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