Table 1 IC50 Table
From: Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells
| Â | MCF-7 | MCF-7/DoxoR | Loewe interaction index | SK-BR-3 | SK-BR-3/NOdoxo | MDA-MB-231 | MDA-MB-231/DoxoR | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  | IC50 (μM) | R sq | IC50 (μM) | R sq | MCF_7 | MCF-7/DoxoR | IC50 (μM) | R sq | IC50 (μM) | R sq | IC50 (μM) | R sq | IC50 (μM) | R sq |
Doxorubicin | 0,04 | 0,96 | 10 | 0,96 | antagonist | n.c. | 10 | 0,95 | 50 | 0,97 | 5 | 0,95 | 75 | 0,94 |
Rottlerin | 0,005 | 0,96 | n.c. | n.c. | Â | Â | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |