Skip to main content
Figure 3 | Molecular Cancer

Figure 3

From: MicroRNA-143 Targets MACC1 to Inhibit Cell Invasion and Migration in Colorectal cancer

Figure 3

Effects of miR-143 on proliferation, migration and invasion of SW620 and SW480 cell lines. (A) Ectopic expression of miR-143 by transfecting miR-143 mimics significantly reduced proliferation of SW620 cells, in comparison with parental and scramble controls (* P < 0.05). (B) Ectopic expression of miR-143 notably inhibited cell migration and invasion of SW620 cells (100 × magnification, * P < 0.05). Inversely, inhibition of miR-143 expression by transfecting miR-143 inhibitors simultaneously (C) promoted proliferation (*P < 0.05) and (D) stimulated cell migration and invasion of SW480 cells, compared with parental and scramble controls (100 × magnification, * P < 0.05). Figure is representative of 3 experiments with similar results.

Back to article page