Figure 5From: Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cellsIllustration of Runx2-mediated epigenetic silencing of BMP-3B in lung cancer cells. The recruitment of Runx2 and Suv39h1 on the BMP-3B locus increases histone H3K9 methylation status resulting in downregulation of BMP-3B expression in lung cancer cells.Back to article page