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Figure 1 | Molecular Cancer

Figure 1

From: Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

Figure 1

Cyclin D1-induced senescence occurs over several weeks. A) Ki67 staining of Irbp-Cyclin D1 pineal sections at the indicated ages (left); immunoflourescence staining for Histone 3 trimethylated at Lysine 9 (H3K9me3) in pineal sections at the indicated ages (middle), with corresponding DAPI staining (right). B) Quantitation of Ki67-positive cells as percent of total pineal cells at indicated ages. C) Immunostaining for Dec1, DcR2, and p15Ink4b, in Irbp-Cyclin D1 pineal glands at the indicated ages.

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Molecular Cancer

ISSN: 1476-4598