Figure 8

Selected miRNAs have common biological pathways. The common biological pathways were identified with the list of predicted targets for the seven co-detected miRNA genes by DAVID Bioinformatics Resources. The percentages of the total identified target genes (y-axis) were plotted against the pathways they regulate (x-axis) with increasing p- value. The pathways in red bars indicate most significant pathways with p- value < 0.05. The green bars indicate the pathways associated with malignancies. Significant biological pathways (*EASE score < 0.05) were selected as the important pathways. *Ease Score Threshold (Maximum Probability): The threshold of EASE Score, a modified Fisher Exact p-value, for gene-enrichment analysis. p-value <0.05 represents strong enrichment in the annotation categories