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Figure 1 | Molecular Cancer

Figure 1

From: The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

Figure 1

RASSF5 methylation and correlation to INRG stage and MYCN amplification. (A) Examples of bisulfite sequencing of RASSF5 in the RASSF5A CpG island: top sequence NB69 and bottom sequence Kelly. CpG sites are underlined and C in the sequence indicates methylation and C/T in the sequence indicate partial methylation. (B) High methylation of RASSF5 is significantly correlated to INRG stage M and MYCN amplification. P-values are indicated in the left upper corner in each graph. Box plot explanation; upper and lower hinges of the box represent the 75th percentile and 25th respectively; whiskers show highest and lowest values. Open circles represent outliers and asterisks show extremes.

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Molecular Cancer

ISSN: 1476-4598