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Table 4 Up-regulation of gene expression following treatment with 5-Aza-dC or 5-Aza-dC/TSA

From: The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

  

Rassf2A*

Rassf4*

Rassf5**

Rassf6**

Rassf7**

Rassf10*

Kelly

AZA

   

UD

  
 

AZA/TSA

 

↑

 

UD

↑

↑

NB69

AZA

  

↑

UD

  
 

AZA/TSA

↑

 

↑

UD

  

SK-N-SH

AZA

   

UD

  
 

AZA/TSA

   

UD

  

SH-SY-5Y

AZA

  

↑

UD

↑

 
 

AZA/TSA

↑

 

↑

UD

  

SK-N-AS

AZA

 

↑

↑

UD

  
 

AZA/TSA

 

↑

 

UD

  

SK-N-BE(2)

AZA

 

↑

↑

UD

  
 

AZA/TSA

 

↑

↑

UD

↑

 

SK-N-DZ

AZA

  

↑

 

↑

↑

 

AZA/TSA

  

↑

 

↑

 

SK-N-FI

AZA

 

↑

    
 

AZA/TSA

↑

↑

    

IMR-32

AZA

 

↑

↑

UD

  
 

AZA/TSA

↑

↑

↑

UD

  
  1. Arrows indicate a more than 2 fold up-regulation of gene expression following treatment.
  2. UD, undetermined - gene transcripts not detected in the PCR amplification.
  3. *qRT-PCR, **End-point RT-PCR.