From: Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer
 |  | CD24 |  | Lyn |  |  |  | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Item | Case | - | + | ++ | +++ | Mean ranks | z//r | P | - | + | ++ | +++ | Mean ranks | z//r | P |
*Gender | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Male | 110 | 2 | 58 | 38 | 12 | 100.35 | −0.336 | 0.737 | 9 | 54 | 38 | 9 | 98.92 | −0.749 | 0.454 |
  Female | 92 | 4 | 40 | 42 | 6 | 102.87 |  |  | 5 | 44 | 34 | 9 | 104.59 |  |  |
*Age(years) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  ≤60 | 112 | 4 | 57 | 45 | 6 | 96.79 | −1.407 | 0.159 | 8 | 56 | 40 | 8 | 99.14 | −0.698 | 0.485 |
  >60 | 90 | 2 | 41 | 35 | 12 | 107.36 |  |  | 6 | 42 | 32 | 10 | 104.43 |  |  |
#Localization | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Right colon | 32 | 1 | 15 | 14 | 2 | 101.44 | 0.02 | 0.990 | 2 | 19 | 8 | 3 | 93.44 | 1.217 | 0.544 |
  Left colon | 68 | 1 | 34 | 29 | 4 | 100.81 |  |  | 4 | 30 | 27 | 6 | 106.05 |  |  |
  Rectum | 102 | 4 | 49 | 37 | 12 | 101.98 |  |  | 8 | 49 | 37 | 9 | 101.04 |  |  |
*Tumor size | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  ≤5 cm | 155 | 4 | 78 | 58 | 15 | 100.82 | −0.333 | 0.739 | 9 | 80 | 54 | 12 | 99.93 | −0.759 | 0.448 |
  >5 cm | 47 | 2 | 20 | 22 | 3 | 103.76 |  |  | 5 | 18 | 18 | 6 | 106.69 |  |  |
&Grade | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  G1 | 99 | 3 | 58 | 34 | 4 |  | 0.255 | 0.000 | 6 | 58 | 30 | 5 |  | 0.233 | 0.000 |
  G2 | 64 | 2 | 30 | 26 | 6 |  |  |  | 6 | 31 | 23 | 4 |  |  |  |
  G3 | 39 | 1 | 10 | 20 | 8 |  |  |  | 2 | 9 | 19 | 9 |  |  |  |
&Tumor stage | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  I | 30 | 2 | 22 | 6 | 0 |  | 0.577 | 0.000 | 3 | 20 | 5 | 4 |  | 0.399 | 0.000 |
  II | 85 | 2 | 62 | 20 | 1 |  |  |  | 8 | 59 | 17 | 3 |  |  |  |
  III | 50 | 1 | 12 | 32 | 5 |  |  |  | 2 | 12 | 31 | 3 |  |  |  |
  IV | 37 | 1 | 2 | 22 | 12 |  |  |  | 1 | 7 | 19 | 8 |  |  |  |
&Invasion depth | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  T1 | 38 | 2 | 24 | 10 | 2 |  | 0.293 | 0.000 | 5 | 22 | 9 | 2 |  | 0.297 | 0.000 |
  T2 | 98 | 1 | 55 | 37 | 5 |  |  |  | 4 | 58 | 30 | 6 |  |  |  |
  T3 | 44 | 2 | 17 | 22 | 3 |  |  |  | 4 | 16 | 20 | 4 |  |  |  |
  T4 | 22 | 1 | 2 | 11 | 8 |  |  |  | 1 | 2 | 13 | 6 |  |  |  |
*Lymph node metastasis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Negative | 130 | 5 | 84 | 38 | 3 | 82.70 | −6.770 | 0.000 | 11 | 81 | 31 | 7 | 86.03 | −5.516 | 0.000 |
  Positive | 72 | 1 | 14 | 42 | 15 | 135.44 |  |  | 3 | 17 | 41 | 11 | 129.43 |  |  |
*Distant metastasis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Negative | 162 | 4 | 96 | 60 | 2 | 88.88 | −6.805 | 0.000 | 13 | 89 | 52 | 8 | 92.71 | −4.694 | 0.000 |
  Positive | 40 | 2 | 2 | 20 | 16 | 152.60 |  |  | 1 | 9 | 20 | 10 | 137.10 |  |  |