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Figure 4 | Molecular Cancer

Figure 4

From: miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer

Figure 4

miR-31 and LOC554202 are epigenetically regulated in breast cancer. (A) Quantitative real-time RT-PCR of miR-31 in the indicated cell lines before and after treatment with 5 Aza-2dC and TSA. miR-16 was used for normalization. (B) Semi-quantitative RT-PCR of LOC554202 after treatment of MDA-MB-231 and BT549 with the de-methylating 5Aza2dC and the de-acetylating Trichostatin A (TSA) agents. Expression of LOC554202 in the untreated cell lines is also shown. GAPDH was used as an internal control.

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