Figure 5
From: Promoter Methylation status of HIN-1 associated with outcomes of ovarian clear cell adenocarcinoma
(A) Cell growth assays of various ES-2 transfectants treated with paclitaxel. Paclitaxel inhibited cell growth of ES-2 transfectants in a dose-dependent manner. In addition, the inhibitory effects of paclitaxel on cell growth were higher in the ES-2 HIN-1 transfectant than in EV-transfected ES-2 cells (circles, p = 0.0001; triangles, p = 0.0005; squares, p = 0.0008). (B) Caspase activities of various ES-2 transfectants. Caspase-3 activities of ES-2 HIN-1 transfectants were higher compared to those of EV-transfected ES-2 cells (for 5 days * p < 0.05; for 7 days, ** p < 0.001).