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Figure 6 | Molecular Cancer

Figure 6

From: Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

Figure 6

IBP knockdown results in increased cisplatin-mediated apoptotic cell death. (A) After a 24 h cisplatin treatment, the cell lysates of the MCF-7/IBP-RNAi cells and the control cells were prepared, and the cytoplasmic marker of apoptosis (cleaved PARP) was detected by western blot. (B) MCF-7/IBP-RNAi cells and the control cells were treated with 2 μg/ml cisplatin to induce apoptosis. The apoptosis was detected at 12 h after cisplatin treatment by Alexa fluor 647 conjugated Annexin V-PI assays.

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Molecular Cancer

ISSN: 1476-4598