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Figure 3 | Molecular Cancer

Figure 3

From: Regulation of colony stimulating factor-1 expression and ovarian cancer cell behavior in vitro by miR-128 and miR-152

Figure 3

A) Luciferase reporter constructs with 2,172nt full length CSF-1 mRNA 3’UTR cloned at the 3’-end of the luciferase mRNA. Either CSF-1 mRNA 3’UTR wild type, Target-A point-mutation (M2573), Target-B point-mutation (M2672), or Target-C point-mutation (M3797) sequences were cloned. B) Only Target-A construct results in an increase in luciferase RNA and C) luciferase activity in Bix3 cells. Bars represent mean ± SD from triplicate experiments.

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Molecular Cancer

ISSN: 1476-4598